David M. Goldenberg Family Endowed Chair in the Institute for Brain Protection Sciences

DAVID M. GOLDENBERG, M.D., and his family established the Goldenberg Family Foundation to make charitable contributions to science, medicine, education, and other philanthropic causes. As a grateful grandfather of a patient treated by George Jallo, M.D., supporting the Institute for Brain Protection Sciences at Johns Hopkins All Children’s Hospital is his commitment to supporting the best care and research for children with brain cancer.

Dr. David Goldenberg is a pioneer in monoclonal antibodies and immunotherapy. He received a degree from the University of Chicago College and Division of Biological Sciences in 1958, a Faculty of Natural Sciences degree (Sc.D.) from the University of Erlangen-Nuremberg in 1965, and his M.D. degree from the University of Heidelberg School of Medicine in 1966. Dr. Goldenberg founded the Center for Molecular Medicine and Immunology in 1983 after a tenure at the University of Kentucky, where he helped launch a cancer research center. In 1985, he was one of the first recipients of the prestigious Outstanding Investigator Grant award, renewed for another seven years in 1992, from the National Cancer Institute. From 1983-2017, Dr. Goldenberg was founder, chairman of the Board, and chief scientist of the publicly-traded biopharmaceutical company, Immunomedics, Inc., which developed antibody-based diagnostic imaging and therapeutic agents for cancer and certain autoimmune diseases. He was the inventor and principal developer of the antibody-drug conjugate, Trodelvy®, approved by the FDA for the treatment of metastatic, recurrent triple-negative breast cancer in 2020, and for metastatic, recurrent urothelial cancer in 2021. He is the inventor of over 300 U.S. patents.

Dr. Goldenberg has published 900 peer-reviewed articles, and edited two books and 14 journal supplements. He has served on editorial boards of over 25 medical journals, being a founding member of several. His articles have been cited about 60,000 times in the medical literature, earning him an “h-index” of 62 (September, 2021). After retiring from full-time research in 2017, he continues to publish invited articles and has recently turned to writing novels focusing on medical research and espionage, and is in the process of publishing several such books. Dr. Goldenberg has five children and 12 grandchildren from his first marriage, and two stepchildren and two step-granddaughters from his current marriage. He resides with his wife, Cynthia, in Delray Beach, Florida.

Held by George Jallo

GEORGE JALLO, M.D., is the vice dean and physician-in-chief at Johns Hopkins All Children’s Hospital. He is also medical director of the Johns Hopkins All Children’s Institute for Brain Protection Sciences. Additionally, Dr. Jallo is a professor of neurosurgery, pediatrics and oncology with Johns Hopkins University School of Medicine.

Dr. Jallo moved to Johns Hopkins All Children’s in 2015 to launch the Institute for Brain Protection Sciences, a multidisciplinary institute that unites clinicians, researchers and educators focused on promoting optimal neurodevelopment and caring for children with injuries and illnesses that can affect the brain.

His areas of expertise include tumors of the brain and spinal cord, intraoperative neurophysiological monitoring for eloquent tumors, and the use of minimally invasive technologies such as endoscopy and keyhole surgery.

Dr. Jallo has published more than 276 peer-reviewed scientific articles, 101 textbook chapters and is co-editor of six textbooks on pediatric neurosurgery, pediatric epilepsy surgery, hydrocephalus and neuroendoscopy. He has given more than 160 international lectures on pediatric neurosurgery around the world with many focusing on his interest of brainstem and spinal cord tumors.

He earned his medical degree at the University of Virginia Medical School and completed his residency in neurosurgery at New York University Medical Center and fellowship in pediatric neurosurgery at Beth Israel Medical Center, Institute for Neurology and Neurosurgery, in New York.