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Mandeep Singh

MANDEEP S. SINGH, M.D., Ph.D., holds the Andreas C. Dracopoulos Professorship in Ophthalmology. He is associate professor of ophthalmology and genetic medicine at the Johns Hopkins School of Medicine, and the founding co-director of the Johns Hopkins Genetic Eye Diseases (GEDi) Center at the Wilmer Eye Institute.

As a retinal physician and vitreoretinal surgeon, he provides care for patients with adult retinal and macular disorders. He leads several gene therapy trials and natural history studies at Johns Hopkins and is the study chair of the Gyrate Atrophy Ocular and Systemic (GYROS) Study, a prospective international natural history study in partnership with the Foundation Fighting Blindness. In addition, he is a member of the Regulatory Endpoints and Trial Design for Inherited Retinal Diseases (REDi) Working Group. His research in genetic ophthalmology also encompasses artificial intelligence and bioethics in genetic eye diseases.

He leads a translational neuroscience laboratory where his research focus is on retinal stem cell therapy, specifically on photoreceptor transplantation, to repair visual deficits in people with degenerative retinal diseases. In relation to this effort, he leads a diverse team aiming to develop surgical techniques for retinal and macular surgery. He is part of the retinal stem cell clinical trial surgical team at the National Eye Institute of the National Institutes of Health.

He is the co-director of the biennial Johns Hopkins Retinal Degeneration and Clinical Electrophysiology Conference series and serves as an advisor to several philanthropic and commercial organizations aiming to further research and development in retinal diseases and therapeutics. He has received several awards including the Ruskell Medal, the Bert M. Glaser Award, and the Macula Society Young Investigator Award.